Gatifloxacin – 5 μg Antibiotic Disc – Bioanalyse

Gatifloxacin – 5 μg Antibiotic Disc – Bioanalyse Overview

The Gatifloxacin – 5 μg Antibiotic Disc – Bioanalyse is a critical diagnostic tool for antimicrobial susceptibility testing. It utilizes a precisely impregnated paper disc containing 5 micrograms of Gatifloxacin, a potent second-generation fluoroquinolone antibiotic. This disc is essential for laboratories employing the standard disc diffusion method to accurately determine the susceptibility of bacterial isolates to Gatifloxacin, guiding effective treatment strategies for a range of bacterial infections.

Gatifloxacin – 5 μg Antibiotic Disc – Bioanalyse Key Features

• Standardized Potency: Each disc contains a precise 5 μg concentration of Gatifloxacin, ensuring consistent and reliable test results.
• Disc Diffusion Method Compatibility: Specifically designed for use in the widely adopted and cost-effective disc diffusion assay.
• Clear Zone of Inhibition Measurement: Facilitates straightforward measurement of zones of inhibition, enabling clear interpretation of bacterial susceptibility.
• Broad-Spectrum Application: Aids in assessing bacterial response to Gatifloxacin, a fluoroquinolone effective against numerous Gram-positive and Gram-negative bacteria.
• Quality Assurance: Manufactured by Bioanalyse, a trusted name, ensuring high-quality and dependable performance for clinical diagnostics.

Technical Specifications

• Antibiotic: Gatifloxacin
• Concentration: 5 μg per disc
• Format: Paper disc
• Methodology: Disc Diffusion (Kirby-Bauer)
• Manufacturer: Bioanalyse
• Application: Antimicrobial Susceptibility Testing (AST)
• Interpretation Standards:
  • Susceptible: ≥ 21 mm
  • Intermediate: 16-20 mm
  • Resistant: < 16 mm

Understanding Results and Limitations

The Gatifloxacin – 5 μg Antibiotic Disc – Bioanalyse is instrumental in identifying bacterial susceptibility. A larger zone of inhibition (≥ 21 mm) indicates susceptibility, while smaller zones suggest intermediate (16-20 mm) or resistant (< 16 mm) bacteria. It’s important to recognize that the disc diffusion method is semi-quantitative. For definitive results, especially in complex cases or for specific bacterial strains like certain Pseudomonas aeruginosa, more precise methods such as broth microdilution or agar dilution may be necessary. Standardized laboratory protocols regarding agar type, incubation temperature, and inoculum density are crucial for accurate interpretation.

About Gatifloxacin

Gatifloxacin is a potent second-generation fluoroquinolone antibiotic known for its bactericidal action against a broad spectrum of bacteria. While generally safe and effective, potential side effects like nausea, diarrhea, and rash can occur. Rare but serious side effects may include seizures or tendonitis. Individuals with known allergies to fluoroquinolones or pre-existing tendon issues should exercise caution.