Norfloxacin – 5 μg Antibiotic Disc – Bioanalyse

Norfloxacin – 5 μg Antibiotic Disc – Bioanalyse Overview

The Norfloxacin – 5 μg Antibiotic Disc – Bioanalyse is a critical diagnostic tool for microbiology laboratories, specifically designed for the disc diffusion method of antimicrobial susceptibility testing. Each disc is precisely impregnated with 5 micrograms of Norfloxacin, a potent fluoroquinolone antibiotic, enabling healthcare professionals to accurately determine the susceptibility of various bacterial strains. This method is essential for guiding effective treatment strategies against a broad spectrum of infections, including urinary tract, gastrointestinal, respiratory, skin, and sexually transmitted infections, ensuring optimal patient care and infection control.

Norfloxacin – 5 μg Antibiotic Disc – Bioanalyse Key Features

• Standardized Norfloxacin Impregnation: Each disc contains a precise 5 μg concentration of Norfloxacin, ensuring consistent and reliable test results.
• Broad-Spectrum Efficacy Assessment: Effectively evaluates bacterial susceptibility to Norfloxacin, a broad-spectrum antibiotic active against both Gram-positive and Gram-negative bacteria.
• User-Friendly Disc Diffusion Method: Facilitates straightforward application in standard laboratory protocols for antimicrobial susceptibility testing.
• High-Quality Disc Material: Manufactured from absorbent paper designed for optimal antibiotic diffusion, contributing to clear zone of inhibition formation.
• Essential for Clinical Diagnosis: A vital component in identifying appropriate antibiotic therapy for a wide range of bacterial infections, aiding in treatment selection and preventing antibiotic resistance.

Technical Specifications

• Product: Antibiotic Susceptibility Disc
• Antibiotic: Norfloxacin
• Potency: 5 μg per disc
• Method of Use: Disc Diffusion Method
• Brand: Bioanalyse
• Application: Antimicrobial Susceptibility Testing (AST)
• Target Bacteria: Gram-positive and Gram-negative bacteria
• Interpretation Guidelines Provided: Includes zone of inhibition measurements for Susceptible (≥ 21 mm), Intermediate (16-20 mm), and Resistant (< 16 mm) classifications.

Understanding Test Results and Limitations

The Norfloxacin – 5 μg Antibiotic Disc – Bioanalyse facilitates the interpretation of bacterial susceptibility based on the zone of inhibition diameter:

• Susceptible: Zone diameter ≥ 21 mm indicates the bacteria are inhibited by Norfloxacin at standard concentrations.
• Intermediate: Zone diameter of 16-20 mm suggests that the bacteria may respond to higher doses or prolonged treatment.
• Resistant: Zone diameter < 16 mm indicates that Norfloxacin is unlikely to be effective against the bacteria.

It is crucial to recognize that the disc diffusion method is a semi-quantitative technique. For definitive and more precise susceptibility data, advanced methods such as broth microdilution or agar dilution are recommended. Furthermore, certain bacterial strains, like some resistant Pseudomonas aeruginosa, may not produce a clear zone of inhibition despite resistance. Standardized laboratory procedures, including agar type, incubation temperature, and inoculum density, are essential for reproducible and accurate results.

Quality Assurance and Product Use

The Norfloxacin – 5 μg Antibiotic Disc – Bioanalyse is manufactured to high standards to ensure reliability in diagnostic testing. While Norfloxacin is generally safe and effective, potential side effects such as nausea, vomiting, diarrhea, abdominal pain, headache, dizziness, and rash can occur. Serious adverse events, though rare, include seizures, tendon rupture, and kidney damage. This product is intended for use by trained laboratory professionals. It is not recommended for individuals with known allergies to Norfloxacin or other fluoroquinolones, nor for children under 18, pregnant, or breastfeeding women.